Simon Kaja Selected Research

1,3- bis(2- hydroxy- 5- trifluoromethylphenyl)urea

1/2019	Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling.
1/2018	Preclinical study of a Kv11.1 potassium channel activator as antineoplastic approach for breast cancer.

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Simon Kaja Research Topics

Disease

5	Neoplasms (Cancer) 10/2020 - 06/2014
5	Glaucoma 03/2017 - 01/2014
4	Dry Eye Syndromes (Dry Eye Syndrome) 01/2022 - 01/2018
3	Macular Degeneration (Age-Related Maculopathy) 11/2021 - 01/2014
3	Disease Progression 08/2021 - 08/2012
3	Ischemia 01/2015 - 07/2003
3	Migraine with Aura (Familial Hemiplegic Migraine) 01/2014 - 03/2004
3	Migraine Disorders (Migraine) 01/2010 - 03/2004
2	Choroidal Neovascularization 11/2021 - 01/2018
2	Breast Neoplasms (Breast Cancer) 01/2019 - 01/2018
2	Cognitive Dysfunction 09/2016 - 10/2013
2	Alzheimer Disease (Alzheimer's Disease) 08/2015 - 12/2013
2	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2015 - 12/2013
2	Nervous System Diseases (Neurological Disorders) 01/2014 - 12/2006
2	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 04/2011 - 07/2003
1	Vascular Remodeling 02/2022
1	Phototoxic Dermatitis (Phototoxicity) 02/2022
1	Hyperglycemia 01/2022
1	Hyperemia 01/2022
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022
1	Inflammation (Inflammations) 01/2022
1	Conjunctivitis 01/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2020
1	Optic Nerve Injuries 04/2020
1	Optic Nerve Diseases (Optic Neuropathy) 04/2020
1	Gliosis 04/2020
1	Necrosis 10/2019
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Triple Negative Breast Neoplasms 01/2019
1	Papilledema 01/2018
1	Edema (Dropsy) 01/2018
1	Keratoconjunctivitis Sicca 01/2018
1	Ischemic Stroke 03/2016
1	Astrocytoma (Pilocytic Astrocytoma) 05/2015
1	Macular Edema 01/2015
1	Chronic Disease (Chronic Diseases) 01/2014

Drug/Important Bio-Agent (IBA)

6	Retinaldehyde (Retinal)IBA 02/2022 - 07/2003
6	Proteins (Proteins, Gene)FDA Link 09/2015 - 08/2012
6	voltage-dependent calcium channel (P-Q type)IBA 01/2014 - 03/2004
5	AntioxidantsIBA 01/2022 - 01/2014
3	Pharmaceutical PreparationsIBA 01/2022 - 12/2013
3	Fluorescein (Funduscein)FDA LinkGeneric 01/2022 - 01/2018
3	Ion Channels (Ion Channel)IBA 01/2019 - 05/2015
3	Homer Scaffolding Proteins (Homer 1)IBA 01/2014 - 07/2003
2	Adenosine (Adenocard)FDA LinkGeneric 02/2022 - 01/2018
2	PorphyrinsIBA 01/2022 - 01/2019
2	Scopolamine (Hyoscine)FDA Link 08/2021 - 01/2018
2	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2020 - 01/2014
2	Potassium Channels (Potassium Channel)IBA 01/2019 - 01/2018
2	1,3- bis(2- hydroxy- 5- trifluoromethylphenyl)ureaIBA 01/2019 - 01/2018
2	palmidrolIBA 03/2016 - 04/2011
2	Biomarkers (Surrogate Marker)IBA 01/2015 - 08/2012
2	Neuroprotective AgentsIBA 04/2011 - 07/2003
1	Adenosine Triphosphate (ATP)IBA 02/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	Streptozocin (Streptozotocin)FDA Link 01/2022
1	Irritants (Vesicants)IBA 01/2022
1	Particulate MatterIBA 01/2022
1	Angiogenic ProteinsIBA 11/2021
1	HydrogelsIBA 11/2021
1	afliberceptIBA 11/2021
1	Polylactic Acid-Polyglycolic Acid CopolymerIBA 08/2021
1	FlavonoidsIBA 08/2021
1	xanthohumolIBA 08/2021
1	Endothelin Receptors (Endothelin Receptor)IBA 10/2020
1	Tyrosine Kinase InhibitorsIBA 10/2020
1	Bosentan (Tracleer)FDA Link 10/2020
1	Gefitinib (Iressa)FDA Link 10/2020
1	ambrisentan FDA Link 10/2020
1	thiazolyl blueIBA 04/2020
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 04/2020
1	Arachidonic Acid (Vitamin F)IBA 10/2019
1	ManganeseIBA 01/2019
1	HCEIBA 01/2019
1	porphyrin aIBA 01/2019
1	Estrogen ReceptorsIBA 01/2019
1	Superoxide DismutaseIBA 01/2019
1	CateninsIBA 01/2019
1	Antineoplastic Agents (Antineoplastics)IBA 01/2018
1	PotassiumIBA 01/2018
1	trabodenosonIBA 01/2018
1	Adenosine A1 ReceptorIBA 01/2018
1	N-Methylaspartate (NMDA)IBA 03/2017
1	Glutamic Acid (Glutamate)FDA Link 03/2017
1	Memantine (Namenda)FDA Link 03/2017
1	tau Proteins (tau Protein)IBA 09/2016
1	Caspase 3 (Caspase-3)IBA 09/2016
1	CaspasesIBA 09/2016
1	PresenilinsIBA 08/2015
1	tert-ButylhydroperoxideIBA 05/2015
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 05/2015
1	Nicotinamide PhosphoribosyltransferaseIBA 01/2015
1	ResveratrolIBA 06/2014
1	Retinal Pigments (Pigments, Visual)IBA 06/2014
1	Protein Isoforms (Isoforms)IBA 01/2014

Therapy/Procedure

10	Therapeutics 11/2021 - 05/2007
2	Lasers (Laser) 11/2021 - 01/2018
1	Cutaneous Administration 01/2018
1	Ophthalmic Administration 01/2018
1	Drug Therapy (Chemotherapy) 01/2014